Optimizing Outcomes for Adults with Spinal Muscular Atrophy: Patient-Centric Strategies for the Interprofessional Treatment Team

Target Audience

This educational initiative is targeted to neurologists, neuromuscular specialists, physical therapists, nurses, nurse practitioners, physician assistants, and adult SMA patients and caregivers.

Learning Objectives

  • Examine the genetic etiology, pathophysiology, and clinical phenotypes of spinal muscular atrophy (SMA) in adult patients.
  • Evaluate unique clinical challenges faced by adults with SMA, emphasizing key distinctions from pediatric SMA.
  • Appraise completed, ongoing, and planned clinical trial data for novel SMA disease-modifying therapies (DMTs) in adult patients, with a focus on FDA-approved agents.
  • Identify how adaptive SMA therapeutic strategies incorporating novel DMTs can fulfill unmet needs and optimize outcomes in adult patients.
  • Use real-world patient cases to design evidence-supported treatment plans for adults with SMA, highlighting the critical importance of patient engagement and shared decision making.

Presented by Creative Educational Concepts, LLC.

Supported through an independent educational grant from Genentech.

Additional Information

PDF icon Handout and References1.6 MB
PDF icon Illustrated Transcript5.03 MB
Course summary
Available credit: 
  • 1.00 ACPE Pharmacy
  • 1.00 AMA PRA Category 1 Credit™
  • 1.00 ANCC
  • 1.00 IPCE
  • 1.00 Participation
Course opens: 
Course expires: 

5 min    Welcome and Introductions/Pre-test

15 min    Characterizing SMA in Adults: Pathophysiology, Phenotype, and Patient Challenges

15 min    Where DMT Meets SMA: Exploring the Evidentiary Base and Clinical Impact of Disease-modifying Therapeutics for Adults

15 min    Power to the Patient: Practical Pearls for Employing Patient-centered Care and Novel Therapies in SMA

10 min    Conversations with the Experts and Q&A/Post-test

Enduring Grand Rounds
United States

Claudia A. Chiriboga, MD, MPH, FAAN
Professor of Neurology​ and Pediatrics​
Division of Child Neurology​
Columbia University Irving ​Medical Center​
New York, NY​



It is the policy of Creative Educational Concepts, LLC, (CEC) to ensure independence, balance, objectivity, and scientific rigor and integrity in all their CME/CE activities. Activity planners, faculty, peer reviewers, and CEC staff must disclose to the participants any relationships with ineligible entities whose products or devices may be mentioned in this CE activity, or with the commercial supporter of this CE activity. An ineligible entity is defined as any entity producing, marketing, re-selling, or distributing health care goods or services consumed by, or used on, patients. Financial relationships may include research grants, consultant fees, travel, advisory boards, consultancy, speakers’ bureaus, other benefits, or having a self-managed equity interest in a company.

CEC has evaluated, identified, and mitigated any potential conflicts of interest through a rigorous content validation procedure, use of evidence-based data/research, and a multidisciplinary peer review process. The following information is for participant information only. It is not assumed that these relationships will have a negative impact on the presentations.

Vanessa Battista, RN, MS, CPNP-PC, CHPPN–has disclosed that she was on the speakers bureau for Clinical Care Options and was an advisor or consultant to Biogen and Novartis.
Mark Huffmyer, PharmD, BCGP, BCACP–has no relevant financial relationships to disclose in relation to the content of this activity.
Claudia A. Chiriboga​, MD, MPH, FAAN​–has disclosed that she receives grants from Biogen, Biohaven, Genentech, Novartis, and Roche. She is also an advisor or consultant to Biogen, Genentech, Novartis, PTC, and Roche.

Peer Reviewer:
Information to come

CEC Staff/Planners:
Susan H. Gitzinger, PharmD, MPA–has no relevant financial relationships to disclose in relation to the content of this activity.
Ashley C. Lilly, MHA–has no relevant financial relationships to disclose in relation to the content of this activity.

Faculty of this CME/CE activity may include discussions of products or devices that are not currently labeled for use by the FDA. The faculty have been informed of their responsibility to disclose to the audience if they will be discussing off-label or investigational uses (any uses not approved by the FDA) of products or devices. CEC, the faculty, and any commercial supporter of this activity do not endorse the use of any product outside of the FDA labeled indications. Medical professionals should not utilize the procedures, products, or diagnosis techniques discussed during this activity without evaluation of their patient for contraindications or dangers of use.

In support of improving patient care, Creative Educational Concepts is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.


This activity was planned by and for the healthcare team, and learners will receive 1 hour of Interprofessional Continuing Education (IPCE) credit for learning and change.


Medicine (ACCME)
CEC designates this live educational activity for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Pharmacy (ACPE)
This application-based activity is approved for 1.0 contact hour (.10 CEUs) of continuing pharmacy education credit (JA0007101-0000-23-005-H01-P)

Nursing (ANCC)
This activity is designated for 1.0 contact hour.

Upon completion of a CE request form, statements of credit for physicians, physician assistants, and nurses will be issued within 30 business days. Pharmacy credit will be reported directly to the National Association of Boards of Pharmacy® (NABP®) CPE Monitor electronic CE tracking system.

Available Credit

  • 1.00 ACPE Pharmacy
  • 1.00 AMA PRA Category 1 Credit™
  • 1.00 ANCC
  • 1.00 IPCE
  • 1.00 Participation
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