Management of neurofibromatosis type 1-associated plexiform neurofibromas (NF1-PNs) has evolved rapidly and now includes indications across age groups. NF1 remains a complex, lifelong condition with diverse and evolving manifestations, requiring clinicians to maintain up-to-date knowledge of diagnostic criteria and clinical presentation. Early features in pediatric patients may be subtle and require longitudinal monitoring, particularly by hematology/oncology nurses. PNs occur in up to 50% of patients and impose substantial quality of life and clinical burdens, including pain, functional impairment, disfigurement, and complications involving critical structures. The advent of mitogen-activated protein kinases 1 and 2 (MEK1/2) inhibitors has transformed management and introduced new requirements for long-term monitoring, toxicity management, and patient education, especially in settings with limited access to specialized care. To improve patient outcomes, clinicians need practical education on how to effectively integrate MEK1/2 inhibitor-based approaches into practice.

In this CE Concepts recorded symposium, faculty will apply NF1 diagnostic and oncologic monitoring guidelines to support early recognition of NF1-PNs in pediatric patients. Learners will be shown how to incorporate MEK inhibitors in the management of NF1-PNs in pediatric patients within care pathways that extend into adult-focused settings through evidence-based monitoring and safety support. Faculty will model the application of interprofessional care coordination and continuity planning strategies in clinical practice to support consistent management of patients with NF1 across pediatric and adult care settings.

In this CE Concepts recorded webcast, expert faculty will review recent developments in the management of advanced or recurrent EC, with a focus on applying emerging clinical evidence, integrating biomarker-driven therapies, and addressing treatment-related toxicities. This program will further explore strategies to enhance interprofessional collaboration, support equitable access to molecular testing and novel therapies, and strengthen patient-centered education to optimize care delivery.

In this CE Concepts recorded Grand Rounds, expert faculty will discuss the latest clinical trial data and guideline recommendations shaping contemporary RCC care. Through a case-based discussion format, faculty will demonstrate how to personalize treatment plans that reflect patient-specific factors and evolving standards of care. Faculty will also share practical approaches to anticipating and managing adverse events, thus equipping multidisciplinary teams to deliver safe, effective, and patient-centered RCC care.