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This Grand Rounds initiative is targeted to cardiologists, endocrinologists, primary care physicians, pharmacists, nurses, nurse practitioners, and physician assistants. Designed to foster meaningful interprofessional and interdisciplinary collaboration, this accredited activity will explore the evolution of SGLT2 inhibition in the era of cardiovascular outcomes trials (CVOTs), as well as evaluate foundational mechanisms linking type 2 diabetes (T2D) to heart failure (HF). Expert faculty will also examine new and emerging CVOT data for SGLT2 inhibitors, including recent approvals and guideline recommendations, and offer insights into how these agents are shifting the HF treatment paradigm and broadening horizons for both diabetic and nondiabetic patients. To reinforce these teaching points within the context of a collaborative approach, attendees will be engaged in a case-based discussion focused on key characteristics of an effective, integrated approach to HF management.

TARGET AUDIENCE
Cardiologists, endocrinologists, primary care physicians, pharmacists, nurses, nurse practitioners, and physician assistants, focused on the integration of new and emerging CVOT data into clinical practice, with an emphasis on collaborative management of heart failure.

LEARNING OBJECTIVES
At the conclusion of this activity, participants will be able to:

• Explore the evolution of SGLT2 inhibition in the CVOT era and evaluate mechanisms linking T2D and heart failure (HF).
• Appraise new and emerging CVOT data for antihyperglycemic agents and compare outcomes data across the type 2 diabetes (T2D) therapeutic classes.
• Examine recently-reported CVOT data for SGLT2 inhibitors, and discuss ways that these agents are shifting the HF treatment paradigm and broadening horizons for both diabetic and nondiabetic patients.
• Using a case-based format, recognize opportunities for cardiologists to collaborate with endocrinologists, primary care providers, and other members of the healthcare team, and identify key characteristics of an integrated approach to HF management.

FACULTY
Javed Butler, MD, MPH, MBA
Patrick H. Lehan Chair in Cardiovascular Research
Professor and Chairman
University of Mississippi Medical Center
Jackson, Mississippi

Jarett D. Berry, MD
Associate Professor of Medicine and Clinical Sciences
Dedman Family Scholar in Clinical Care
Division of Cardiology
University of Texas Southwestern Medical Center
Dallas, Texas

Muthiah Vaduganathan, MD, MPH
Harvard Medical School
Brigham and Women’s Hospital
Cardiovascular Medicine
Boston, Massachusetts

ACCREDITATION
1-hour presentation providing up to 1.0 ACCME/ANCC/ACPE/AAPA credit