EACCME

Maintaining Patient QoL through Optimal Management of ADC-Associated AEs

Patients with HER2-negative metastatic breast cancer (MBC) who receive antibody-drug conjugates (ADCs) may experience a spectrum of adverse events (AEs) that can lower their quality of life (QoL). Patients and caregivers rely on their care team…

Clinical Trial Data with ADCs: New Options for HER2-Negative MBC

The rapidly shifting therapeutic landscape for HER2-negative metastatic breast cancer (MBC) challenges clinicians to stay up-to-date on emerging clinical trial data, as well as recommendations on therapy selection and sequencing. Unfamiliarity with antibody-drug conjugate (ADC) treatment…

ADCs and Chemotherapy: More Different Than You Might Expect in HER2-Negative MBC

Antibody-drug conjugates (ADCs) have recently been approved to treat HER2-negative metastatic breast cancer (MBC). In an ADC, a cytotoxic chemotherapeutic agent is conjugated to a monoclonal antibody directed against a tumor-associated antigen. Conjugation fundamentally alters tissue…

ADCs in HR+/HER2- mBC: Managing AEs

Patients with HR-positive/HER2-negative metastatic breast cancer (mBC) who receive antibody-drug conjugates (ADCs) have a unique spectrum of adverse events (AEs) that can lower quality of life (QoL). Patients and caregivers rely on health care providers for…

ADCs in HR+/HER2- mBC: Guidelines and Expert Consensus

The rapid evolution of the HR-positive/HER2-negative treatment landscape has led to multiple revisions of clinical practice guidelines. Health care practitioners are challenged to consider the most current data while fine-tuning therapy selections, but also to incorporate…