This session will review the totality of emerging evidence for immune checkpoint inhibitors (ICIs) in the hepatocellular carcinoma (HCC) and biliary tract cancer (BTC) management calculus. Faculty will highlight the paradigmatic change ICIs have achieved, emphasize key teaching points for real-world use, and evaluate adaptive clinical trial designs and study schemas being used to investigate ICI-based treatment regimens in HCC and BTC on a prospective basis.
Supported through an independent educational grant from AstraZeneca.
Immuno-oncology (IO) specialty clinicians and researchers.
In support of improving patient care, Creative Educational Concepts, LLC, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.
Creative Educational Concepts, LLC, designates this enduring activity for a maximum of 1.00 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
It is the policy of Creative Educational Concepts, LLC, (CEC) to ensure independence, balance, objectivity, and scientific rigor and integrity in all their CME/CE activities. Activity planners, faculty, peer reviewers, and CEC staff must disclose to the participants any relationships with ineligible entities whose products or devices may be mentioned in this CE activity, or with the commercial supporter of this CE activity. An ineligible entity is defined as any entity producing, marketing, re-selling, or distributing health care goods or services consumed by, or used on, patients. Financial relationships may include research grants, consultant fees, travel, advisory boards, consultancy, speakers’ bureaus, other benefits, or having a self-managed equity interest in a company.
CEC has evaluated, identified, and mitigated any potential conflicts of interest through a rigorous content validation procedure, use of evidence-based data/research, and a multidisciplinary peer review process. The following information is for participant information only. It is not assumed that these relationships will have a negative impact on the presentations.
James J. Harding, MD–has disclosed that he receives research support from Boehringer Ingelheim, Bristol Myers Squib, Codiak, CytomX, Eli Lilly, Genoscience, Incyte, Loxo @ Lilly, Novartis, Polaris, and Yiviv. He is also an advisor or consultant to Bristol Myers Squib, Eisai, Exelexis, Hepion, Imvax, Medivir, QED, and Zymewor.
R. Katie Kelley, MD–has disclosed that she receives research support from Agios, AstraZeneca, Bayer, Bristol Myers Squibb, Eli Lilly, EMD Serono, Exelixis, Genentech/Roche, LOXO oncology, Merck, Novartis, QED therapeutics, Relay Therapeutics, Surface Oncology, and Taiho. She also is an advisor or consultant to Exact Sciences and Kinnate. She is an advisor or consultant to Agios, AstraZeneca, Exelixis, Ipsen, and Merck with compensation to her institution and her institution receives grant funding from Partner Therapeutics.
Riad Salem, MD, MBA–has disclosed that he is an advisor or consultant to AstraZeneca, Autem, Bard, Boston Scientific, Cook, Eisai, Genentech, Merck, and Merit.
Darren Cowzer, MD–has no relevant financial relationships to disclose in relation to the content of this activity.
Susan H. Gitzinger, PharmD, MPA–has no relevant financial relationships to disclose in relation to the content of this activity.
Rebecca Weaver, CHCP–has no relevant financial relationships to disclose in relation to the content of this activity.
Faculty of this CME/CE activity may include discussions of products or devices that are not currently labeled for use by the FDA. The faculty have been informed of their responsibility to disclose to the audience if they will be discussing off-label or investigational uses (any uses not approved by the FDA) of products or devices. CEC, the faculty, and any commercial supporter of this activity do not endorse the use of any product outside of the FDA labeled indications. Medical professionals should not utilize the procedures, products, or diagnosis techniques discussed during this activity without evaluation of their patient for contraindications or dangers of use.
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