Digging Deep into the Genome: What Genetic Testing Can (and Can’t) Tell Us about Ovarian Cancer


Joseph W. Carlson, MD, PhD
Professor of Clinical Pathology
Department of Pathology, USC Keck School of Medicine
University of Southern California, Los Angeles, CA
Beth Y. Karlan, MD
Professor and Vice Chair of Women's Health Research
Department of Obstetrics and Gynecology, David Geffen School of Medicine at UCLA
Director, Cancer Population Genetics
UCLA-Jonsson Comprehensive Cancer Center, Los Angeles, CA

Statement of Need

Expert faculty for this 30-minute webinar will include a pathologist and a gynecologic oncologist. Faculty will summarize the latest guidelines on genes that should be tested in ovarian cancer and the appropriate identification of patients who should receive testing. The benefits and limitations of various testing technologies will be discussed (e.g., multigene panel testing), as well as the utility of measuring other indicators of genomic instability (e.g., HRD, LOH, etc.). Additionally, there will be a focus on strategies to properly interpret results as a means to identify patients who may benefit from PARP inhibitors.

Learning Objectives

  • Review risk factors to guideline‐recommended genetic testing and treatment in ovarian cancer, including access to care, race, comorbidities, socioeconomic factors, education, and insurance status.
  • Evaluate challenging ovarian cancer cases focusing on key health equity issues and strategies that the multidisciplinary team can employ to help mitigate modifiable healthcare disparities in their patients.

Supported by

Supported through an independent educational grant from GlaxoSmithKline.

Target Audience

Gynecologic oncologists, medical oncologists, gynecologists, and other members of the healthcare team who manage patients with ovarian cancer.

Credit Information

Jointly Accredited Provider

In support of improving patient care, Creative Educational Concepts, LLC, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

AMA PRA Category 1 Credit(s)™

Creative Educational Concepts, LLC, designates this enduring activity for a maximum of 0.5 AMA PRA Category 1 Credit(s). Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Disclosure Declaration

It is the policy of Creative Educational Concepts, LLC, (CEC) to ensure independence, balance, objectivity, and scientific rigor and integrity in all their CME/CE activities. Activity planners, faculty, peer reviewers, and CEC staff must disclose to the participants any relationships with ineligible entities whose products or devices may be mentioned in this CE activity, or with the commercial supporter of this CE activity. An ineligible entity is defined as any entity producing, marketing, re-selling, or distributing health care goods or services consumed by, or used on, patients. Financial relationships may include research grants, consultant fees, travel, advisory boards, consultancy, speakers’ bureaus, other benefits, or having a self-managed equity interest in a company.

CEC has evaluated, identified, and mitigated any potential conflicts of interest through a rigorous content validation procedure, use of evidence-based data/research, and a multidisciplinary peer review process. The following information is for participant information only. It is not assumed that these relationships will have a negative impact on the presentations.

Beth Y. Karlan, MD–has disclosed that she is an advisor or consultant to Bluestar Genomics, F. Hoffmann-LaRoche, Ltd., FUJIFILM Pharmaceuticals USA, Grail, Inc., and Mercy BioAnalytics, Inc. She also receives research support from Aravive, Inc., Immunogen, Incyte Corporation, Merck & Co., Inc., Mersana Therapeutics, and Zentalis Pharmaceuticals.

Joseph W. Carlson, MD, PhD–has no relevant financial relationships to disclose in relation to the content of this activity.

Peer Reviewer:
Pamela Peters, MD–has disclosed that she receives grant funding from Foundation for Women’s Cancer.

CEC Staff/Planners:
Susan H. Gitzinger, PharmD, MPA–has no relevant financial relationships to disclose in relation to the content of this activity.
Tina L. Trieu, PharmD–has no relevant financial relationships to disclose in relation to the content of this activity.
Jessica Hall–has no relevant financial relationships to disclose in relation to the content of this activity.

Faculty of this CME/CE activity may include discussions of products or devices that are not currently labeled for use by the FDA. The faculty have been informed of their responsibility to disclose to the audience if they will be discussing off-label or investigational uses (any uses not approved by the FDA) of products or devices. CEC, the faculty, and any commercial supporter of this activity do not endorse the use of any product outside of the FDA labeled indications. Medical professionals should not utilize the procedures, products, or diagnosis techniques discussed during this activity without evaluation of their patient for contraindications or dangers of use..

Obtaining Credit

Post-tests, credit request forms, and activity evaluations must be completed online (requires free account activation), and participants can print their certificate or statement of credit immediately (75% pass rate required). This website supports all browsers except Internet Explorer for Mac. Visit the Creative Educational Concepts Privacy Policy page for complete information about our privacy policy and practices.

Questions about this activity?

Call us at 859-260-1717  •  info@ceconcepts.com


Call us at 859-260-1717  •  info@ceconcepts.com

Digging Deep into the Genome: What Genetic Testing Can (and Can’t) Tell Us about Ovarian Cancer
Activity Date: 07/12/2022