Alexander Lesokhin, MD

Memorial Sloan Kettering Cancer Center
Myeloma Service, Division of Hematologic Oncology, Department of Medicine
New York, NY

Dr. Lesokhin is an Attending Physician in the Myeloma Service at Memorial Hospital, Division of Hematologic Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY. Dr. Lesokhin received his medical degree from Albert Einstein College of Medicine. After receiving his Medical Degree, he completed an Internal Medicine residency at New York-Presbyterian Hospital/Columbia University Medical Center, followed by a Hematology/Oncology Fellowship at Memorial Sloan Kettering Cancer center. He is Board Certified in Internal Medicine, Medical Oncology, and Hematology.

Dr. Lesokhin is a physician-scientist focused on the study of tumor immunology with a specific interest in developing innovative ways to use the immune system to treat cancer. He leads the immunotherapy clinical trials as a clinician in Memorial Sloan Kettering’s immunotherapeutic Clinical Core. He has been involved in the development and implementation of several vaccines studies and immunomodulatory antibody clinical studies. This work involves ongoing monitoring of immune responses against tumor antigens (ex. cancer testis antigens) and development of biomarkers of clinical outcome following immunomodulatory antibody therapy in multiple tumor types.

In the lab, he focuses on the characterization of myeloid derived suppressor cells (MDSC) and the implications of these cells for the development of adaptive immune responses against melanoma and other cancers. Dr. Lesokhin has been awarded funding by the American Cancer Society and the Melanoma Research Alliance to continue work in the laboratory and to pursue clinically relevant translational studies focused on MDSC.

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