Identification and Surveillance of Individuals with VHL Disease

Faculty

Eric Jonasch, MD
Professor
Department of Genitourinary Medical Oncology
University of Texas MD Anderson Cancer Center
Houston, TX

Statement of Need

Von Hippel-Lindau (VHL) disease is a rare, heritable condition in which approximately 80% of affected individuals have an affected parent, underscoring the critical importance of early identification and surveillance. However, its rarity and variable presentation can make timely recognition and management challenging. Gaps persist in the consistent application of current surveillance strategies and in recognizing at-risk patients with and without a known family history, highlighting the need for education that bridges these real-world challenges.

In this first of two CE Concepts BriefCases in this series, expert faculty will discuss how to assess current surveillance practices and apply strategies to identify individuals at risk for VHL. Through realistic clinician-patient interactions and data-driven insights, this innovative format connects evidence to real-world patient journeys, equipping clinicians to confidently recognize early signs of VHL and implement effective surveillance to support timely detection and improved outcomes.

Learning Objectives

At the conclusion of this activity, learners will be able to better:

  • Evaluate current surveillance approaches for the identification of VHL disease
  • Engage an interdisciplinary team of professionals for the care of patients with VHL disease or VHL-associated tumors

Financial Support

This activity is supported through an independent educational grant from Merck & Co., Inc., Rahway, NJ, USA. 

Target Audience

  • Primary: Medical oncologists, oncology nurses, and oncology nurse practitioners (NPs) and physician associates (PAs)
  • Secondary: Genetic counselors, medical geneticists, and other members of the VHL treatment team

Credit Information

Jointly Accredited Provider

In support of improving patient care, Creative Educational Concepts, LLC, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

Physicians (ACCME) 0.5

Creative Educational Concepts, LLC, designates this enduring material for a maximum of  0.50 AMA PRA Category 1 Credit(s). Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Nurses (ANCC) 0.5

This activity is designated for 0.50 contact hours.

Note to Nurse Practitioners: The content of this CNE activity pertains to Pharmacology.

American Nurses Credentialing Center with ILNA

This activity is designated for 0.50 contact hours.

The program content has been reviewed by the Oncology Nursing Certification Corporation (ONCC) and is acceptable for recertification points in the following ILNA subject areas:

OCN®
Care Continuum

CBCN® 
Care Continuum

CPHON® 
Care Continuum
Oncology Nursing Practice

AOCNP® 
​Care Continuum
Roles of the APRN

Interprofessional (IPCE) 0.5

This activity was planned by and for the healthcare team, and learners will receive 0.50 Interprofessional Continuing Education Credit for learning and change.

Physician Assistants (AAPA) 0.5

Creative Educational Concepts, LLC, has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with AAPA CME Criteria. This activity is designated for 0.50 AAPA Category 1 CME credits. Approval is valid until 11/25/2026. PAs should only claim credit commensurate with the extent of their participation.

ABIM MOC

Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 0.50 MOC points in the American Board of Internal Medicine’s (ABIM) Maintenance of Certification (MOC) program. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.

MIPS Improvement Activity

Completion of this accredited CME activity meets the expectations of an Accredited Safety or Quality Improvement Program (IA_PSPA_28) for the Merit-based Incentive Payment Program (MIPS). Clinicians should submit their improvement activities by attestation via the CMS Quality Payment Program website.

Royal College MOC

Through an agreement between the Accreditation Council for Continuing Medical Education and the Royal College of Physicians and Surgeons of Canada, medical practitioners participating in the Royal College MOC Program may record completion of accredited activities registered under the ACCME’s “CME in Support of MOC” program in Section 3 of the Royal College’s MOC Program.

Disclosure Declaration

It is the policy of CE Concepts, LLC, to ensure independence, balance, objectivity, and scientific rigor and integrity in all of their CE activities. Faculty must disclose to the participants any relationships with commercial companies whose products or devices may be mentioned in faculty presentations, or with the commercial supporter of this CE activity. CE Concepts, LLC, has evaluated, identified, and mitigated any potential conflicts of interest through a rigorous content validation procedure, use of evidence-based data/research, and a multidisciplinary peer review process. The following information is for participant information only. It is not assumed that these relationships will have a negative impact on the presentations.

Dr. Jonasch reports the following financial relationships:

Consultant: Arcus Biosciences, Inc.; AVEO Pharmaceuticals, Inc.; Eisai Inc.; Exelixis, Inc.; Ipsen Pharma; Merck & Co., Inc.; NiKang Therapeutics, Inc.; Novartis Pharmaceuticals Corporation; Takeda Pharmaceutical Company Limited; and Telix Pharmaceuticals Limited

Research Support: Abbvie Inc.; AVEO Pharmaceuticals, Inc.; Bristol Myers Squibb Company; Corvus Pharmaceutical; Merck & Co., Inc.; NiKang Therapeutics, Inc.; ProfoundBio; and Telix Pharmaceuticals Limited

Speakers Bureau: DAVA Oncology

The following individuals have no financial relationships to disclose: 

Alaa Bawaneh, MD, PhD (Peer Reviewer)
Michael Franks, APRN, AGACNP-BC, FNP-BC (Peer Reviewer)
Susan Perry (Planning Committee)
Taylor Wallace, PhD (Planning Committee)
Kashemi D. Rorie, PhD (Planning Committee)
Scott J. Hershman, MD, FACEHP, CHCP (Planning Committee)
Sandra Caballero, PharmD (Planning Committee)
Sharon Tordoff (Planning Committee)

*All identified conflicts of interest have been mitigated.

Unlabeled Use Disclosure
Faculty of this CME/CE activity may include discussions of products or devices that are not currently labeled for use by the FDA. The faculty have been informed of their responsibility to disclose to the audience if they will be discussing off-label or investigational uses (any uses not approved by the FDA) of products or devices. CE Concepts, LLC, the faculty, planners, and reviewers do not endorse the use of any product outside of the FDA labeled indications. Medical professionals should not utilize the procedures, products, or diagnosis techniques discussed during this activity without evaluation of their patient for contraindications or dangers of use.

Obtaining Credit

Post-tests, credit request forms, and activity evaluations must be completed online (requires free account activation), and participants can print their certificate or statement of credit immediately (0% pass rate required). This website supports all browsers except Internet Explorer for Mac.

Obtaining Credit

Post-tests, credit request forms, and activity evaluations must be completed online (requires free account activation), and participants can print their certificate or statement of credit immediately (75% pass rate required). This website supports all browsers except Internet Explorer for Mac.

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Questions about this activity?

Call us at 859-260-1717  •  info@ceconcepts.com

BC-141-112525-44

Call us at 859-260-1717  •  info@ceconcepts.com

Identification and Surveillance of Individuals with VHL Disease
Activity Date: 11/25/2025