Accreditation Information

CPE

In support of improving patient care, Creative Educational Concepts is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

This application-based activity is approved for 1.50 contact hours (0.150 CEUs) of continuing pharmacy education credit (UAN UAN 0245-0000-17-013-L01-P).

Other

Creative Educational Concepts, Inc. certifies this activity for 1.50 hours of participation.

Objectives

At the conclusion of this application-based activity, participants will be able to:

1. Analyze the main signaling pathways and key mechanisms in DNA damage repair and how deficiencies in these pathways can lead to tumor proliferation and growth.

2. Examine the pharmacology of PARP inhibitors and how these agents induce tumor cell death by exploiting the concept of “synthetic lethality” in cells with BRCA mutations.

3. Explore evolving data regarding the efficacy and adverse event profiles of PARP inhibitors currently approved and in clinical development for patients with ovarian, breast, prostate, and pancreatic cancers.

4. Using a case-based approach, assess challenging questions regarding PARP inhibitors and discuss the ways that the oncology pharmacist can optimize therapy, anticipate adverse effects, and improve adherence.  

Target Audience

Pharmacists attending the American Society of Health-System Pharmacists Annual Meeting (ASHP) Annual Meeting interested in learning the latest clinical and scientific advances in targeting DNA damage response (DDR), including updates on the current and emerging prospects of poly-ADP ribose polymerase (PARP) inhibitors. 

Faculty Disclosure

Planner and Faculty Disclosures

In accordance with the Food and Drug Administration, the speakers have disclosed that there is the potential for discussions concerning off-label uses of a commercial product/device during this educational activity.

Any person who may contribute to the content of this continuing education activity must disclose relevant relationships (and any known relationships of their spouse/partner) with commercial interests whose products or services are discussed in educational presentations. A commercial interest is defined as any entity producing, marketing, re-selling, or distributing health care goods or services consumed by, or used on, patients. Relevant relationships include receiving from a commercial interest research grants, consultant fees, travel, other benefits, or having a self-managed equity interest in a company.

Disclosure of a relationship is not intended to suggest or condone any bias in any presentation but is made to provide participants with information that might be of potential importance to their evaluation of a presentation.

Planner: 
Vanessa Carranza, PharmD - has no relevant financial relationships to disclose in relation to the content of this activity.

Authors/Presenters:

Jason Bergsbaken, PharmD, BCOP - has no relevant financial relationships to disclose in relation to the content of this activity.

James M. Ford, MD - has no relevant financial relationships to disclose in relation to the content of this activity.

Judith A. Smith, PharmD, BCOP, CPHQ, FCCP, FISOPP (Activity Chair) -  has no relevant financial relationships to disclose in relation to the content of this activity.

Peer Reviewer:

Allison Guyton, PharmD, BCOP, BCPS - has no relevant financial relationships to disclose in relation to the content of this activity.